Meet Our Medical Advisors
Meet the amazing men and women who help babies affected by Congenital Diaphragmatic Hernia not only in the Operating Room, Intensive Care Unit and the Laboratory but they help families by volunteers for our charity as well.
Our Medical Advisory Board participates in our CDH Conferences, proofs our materials and research projects, participates in other events such as the International Day of Congenital Diaphragmatic Hernia Awareness, lobbies with us for more research funding and works with our charity and other members of ACDHO to better the CDH Community
N. Scott Adzick, MD, MMM, FACS, FAAP – Children’s Hospital of Philadelphia
Dr. Adzick is the C. Everett Koop Professor of Pediatric Surgery at CHOP and the founder and director of the Hospital’s Center for Fetal Diagnosis and Treatment. He also serves as CHOP’s Surgeon-in-Chief, Director of the Division of Pediatric General, Thoracic and Fetal Surgery, and Professor of Pediatrics, Obstetrics and Gynecology at the University of Pennsylvania School of Medicine.
Patricia Donahoe, MD – Massachusetts General Hospital
Patricia K. Donahoe is Director of Pediatric Surgical Research Laboratories and Chief Emerita of Pediatric Surgical Services at Massachusetts General Hospital where she has worked virtually her entire career, and the Marshall K. Bartlett Professor of Surgery (Tenured) at Harvard Medical School. She received her MD from Columbia University in New York City, New York, and BS from Boston University in Boston, Massachusetts where she currently serves on the Board of Trustees. She is a member and past Chair of the Scientific Advisory Board at St. Judes Medical Center and has been a member of the Scientific Advisory Board at Memorial Sloan-Kettering Cancer Center and of the NICHD National Advisory Council. She has published over 230 peer-reviewed publications in developmental biology concentrating on Mullerian Inhibiting Substance as a potential anticancer agent against human ovarian carcinomas, as well as the genetics of sex differentiation and a number of other congenital anomalies for which she has been steadily funded by the NIH. Dr. Donahoe and her colleagues, particularly David MacLaughlin, hold a number of patents on MIS. They purified the human MIS, cloned the MIS gene and that of its receptors, studied their regulation and their roles in the growth, diagnosis, and treatment of ovarian and other reproductive tumors, and used MIS as a marker in the diagnosis of human tumors in human intersex disorders.
She is a member of the National Academy of Sciences, Institute of Medicine of the National Academy of Sciences, and American Academy of Arts and Sciences. Dr. Donahoe served as President of the Boston Surgical Society and is President-elect of the American Pediatric Surgical Association. She has received many research prizes and honorary degrees for her work on MIS, but her fondest dream is to see it developed as a therapeutic for ovarian and other reproductive cancers.
Wendy Chung, MD, PhD - Columbia Presbyterian / DHREAMS
Wendy Chung, MD, PhD, is a clinical and molecular geneticist who directs the clinical genetics program at Columbia University and currently has a grant from the Children's Cardiomyopathy Foundation to identify new genes for infantile cardiomyopathy. The goal of her research is to identify new genes for susceptibility to cardiac disease and to develop individualized risk assessment, prevention, and therapeutic interventions for HCM. Clinically, she directs programs in risk assessment for cardiomyopathy and arrhythmias and develops novel molecular diagnostic methods to improve genetic testing including pre-implantation genetic diagnosis for family planning.
She lectures and writes on the legal and social issues raised by genetic testing in asymptomatic individuals, disparities is access to genetic care, confidentiality and privacy of genetic information, and defining conditions for which prenatal genetic testing is or is not appropriate. A recipient of the American Academy of Pediatrics Young Investigator Award and the Herbert Irving assistant professor of pediatrics and medicine, Dr. Chung received her B.A. in biochemistry and economics from Cornell University, her M.D. from Cornell University Medical College, and her Ph.D. from The Rockefeller University in genetics.
Jan Deprest, MD, PhD - University Hospital Gasthuisberg, Leuven, Belgium
David Kays, MD – Shands for Kids / University of Florida at Gainesville
Dr. Kays has led an effort to improve outcome from congenital diaphragmatic hernia (CDH) that has made UF Health Shands Children’s Hospital one of the recognized world leaders in the clinical care of this condition. Utilizing a protocol focused on strict protection of the infant’s lungs, survival in newborns with CDH delivered at UF Health is now close to 90 percent.
Dr. Kays has carefully documented and analyzed this experience and is actively investigating new methods to further improve outcomes. He directs the Shand’s ECMO program and holds leadership positions in the Extracorporeal Life Support Organization. He is currently involved in a collaboration with the hopes of improving brain protection in children with CDH and those on ECMO. Dr. Kays’ main research interests include Congenital Diaphragmatic Hernias, Neonatal Ventilation, Congenital Anomalies, Pectus Carinatum and Pectus Excavatum.
Kevin Lally, MD, MS, FACS - University of Texas Medical School at Houston
Dr. Lally is the A.G. McNeese Chair in Pediatric Surgery, Richard Andrassy Distinguished Professor and Chairman of the Department of Pediatric Surgery. He is Surgeon-in-Chief of the Children's Memorial Hermann Hospital and Director of the ECMO Program. Dr. Lally completed his Pediatric Surgery Training at the Children's Hospital of Los Angeles and is board certified in Surgery, Critical Care and Pediatric Surgery. Dr. Lally is one of the world’s leading experts in Congenital Diaphragmatic Hernias (CDH). He developed and runs the CDH Registry, which in an international consortium that has prospectively collected data on over 6,000 infants with this rare anomaly. He is actively involved in student and resident education and the Center for Clinical Trials and Evidence Based Surgery. Dr. Lally has been principal investigator or co-investigator on several clinical trials.
Paul Losty, MD FRCSI FRCS(Eng) FRCS(Ed) FRCS(Paed) – Liverpool University, UK
Internal Collaborations • University of Liverpool, Human Anatomy and Cell Biology, Dr D Moss • University of Liverpool, Child Health, Mr EC Jesudason
• University of Liverpool, Biological Sciences, School of, Prof MR White and Dr D Spillar
• University of Liverpool, Biological Sciences, School of, Prof DG Fernig and Prof J Turnbull
Research Awards: Principal Investigator • Cellular Models for Studying Lung Abnormalities in Congenital Diaphragmatic Hernia. • Exploiting mechanical stimuli to increase prenatal growth of the hypoplastic lung.
• Physiology of the pulmonary pacemaker: a new regulator of prenatal lung growth.
• Exploiting mechanical stimuli to increase prenatal growth of the hypoplastic lung.
• Sonographic measurement of peristalsis in normal human fetal airway.
• Endothelial-vascular smooth muscle interactions in the hypertensive hypoplastic perinatal lung.
Steadman McPeters, CPNP – Huntsville Alabama, Pediatric Surgery Nurse Clinician
Bio coming soon.
Doug Miniati, MD – University of California, San Francisco
Neonates with congenital diaphragmatic hernia (CDH) represent a fascinating challenge to those who are involved in their care. Great strides have been made to improve our perinatal and perioperative care for these patients, leading to increased survival. However, a wide spectrum of disease severity exists, from the few, who are cured with a single procedure, to the majority, who suffer long-term sequelae related pulmonary insufficiency and gastrointestinal dysfunction. Much remains to be understood regarding both normal and abnormal lung development and response to various stimuli, and more importantly, regarding the advancement of new and effective therapeutic strategies for patients with CDH.
The Miniati lab focuses on 1) furthering our understanding of the mechanisms of CDH-associated lung hypoplasia in both teratogenic and genetic mouse models, and 2) developing prenatal pharmacologic treatments and in utero mechanical means to promote optimal lung function in the ovine CDH model. Other developing areas of interest include the human genetics of CDH and continued long-term outcomes analyses of children in our multidisciplinary CDH clinic. Through collaborations with colleagues in the Lung Biology Center, the UC Berkeley/UCSF Bioengineering Program, and the divisions of neonatology and pediatric intensive care, we are gaining more insight into how this disease occurs and how to treat it, ultimately leading to improved quality of life for both patients and their families.
Henry Rice, MD – Duke University Medical Center
Division Chief, Pediatric General SurgeryDepartments / Divisions
Surgery / Pediatric General Surgery
Pediatrics / Pediatrics-Chairman Office
Edmund Yang, MD – OSF / Univeristy of Illinois
Title(s): Clinical Associate Professor of Surgery - University of Illinois College of Medicine at Peoria
Medical Education: Vanderbilt University (Nashville, TN)
Internship(s): General Surgery - University of California at San Francisco (San Francisco, CA; 1993-1994)
Residency: General Surgery - University of California at San Francisco (San Francisco, CA; 1994-2001)
Fellowship(s): Pediatric Surgery - Boston Children's Hospital (Boston, MA; 2001-2003)
Board Certification(s): Pediatric Surgery - American Board of Surgery
Professional Certification(s): Advanced Trauma Life Support (ATLS)
Clinical Interests: Fetal Intervention, Neonatal Surgery, Minimally Invasive Surgery
Professional Memberships: American Academy of Pediatrics, National Board of Medical Examiners, American Board of Surgery, American Pediatric Surgical Association, International Pediatric Endosurgery Group, International Fetal Medicine & Surgery Society
Awards & Recognition: Farley Fellowship - Boston Children's Hospital (2002), Chief Resident - University of California at San Francisco General Surgery Department (2000-2001), Von L. Meyer Fellowship Fund - Boston Children's Hospital (2001), British Association of Pediatric Surgeons Award (1998), Medical Scientist Training Program Award - National Institute of General Medicine (1987-1993), Guest Research Award - National Heart, Lung, & Blood Institute (1986-1987), Cystic Fibrosis Foundation Award (1996-1998), Former Principal Investigator - Management of Myelomeningocele Study
Past Medical Advisors for CHERUBS have included:
- Jay M. Wilson, MD
- Michael R. Harrison, MD
- Beth Zimmerman, RN
- Prem Puri, MD
- Jacob Langer, MD
- Vincent Adolph, MD
- Aviva Katz, MD
- Lesli Taylor, MD